WebJun 10, 2005 · The BTB domain (also known as the POZ domain) is a versatile protein-protein interaction motif that participates in a wide range of cellular functions, including transcriptional regulation, cytoskeleton dynamics, ion channel assembly and gating, and targeting proteins for ubiquitination. Several BTB domain structures have been … WebWithin all these proteins the WD-repeat domains are thought to have two common features: the domain folds into a beta propeller; and the domains form a platform …
WW domain-containing proteins: retrospectives and the …
WebThe WD-repeat-containing proteins form a very large family that is diverse in both its function and domain structure. Within all these proteins the WD-repeat domains are thought to have two common features: the domain folds into a beta propeller; and the domains form a platform without any catalytic activity on which multiple protein … WebAll endophilin proteins have N-BAR domains that mediate dimerization and membrane curvature sensing and generation, and a C-terminal SH3 domain that binds to proline-rich regions in target proteins (Gallop et al., 2006 ). The rapid initiation of the pathway is explained by the pre-enrichment of endophilin on the plasma membrane. ceo punjab
PNPLA3 - Wikipedia
WebThis gene encodes a pyrin-like protein which contains a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with pyrin domain (PYD) of apoptosis-associated speck-like protein containing a CARD (ASC). WebFNDC3B codes for an extracellular matrix protein involved in several signaling pathways, including PI3-kinase/Akt, Rb1 and TGFβ signaling.11 TGF beta is known to induce extracellular matrix remodeling and can alter the cytoskeleton though both the canonical Smad and noncanonical signaling pathways.110 Experiments have shown that variation … WebWW domains are protein modules that mediate protein-protein interactions through recognition of proline-rich peptide motifs (PRM) and phosphorylated serine/threonine … ceo punjab name